2014
1. Shen EZ, Song CQ, Lin Y, Zhang WH, Su PF, Liu WY, Zhang P, Xu JJ, Lin N, Zhan C, Wang XH, Yu Shyr, Cheng HP, Dong MQ. Mitoflash frequency in early adulthood predicts lifespan in caenorhabditis elegans. Nature. 2014, 508(7494): 128-132.
2. Lu Z, Xu X, Fassett J, Kwak D, Liu X, Hu X, Wang H, Guo H, Xu D, Yan S, McFalls EO, Lu F, Bache RJ, Chen Y. Loss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 kinase protects mice from pressure overload-Induced congestive heart failure without affecting ventricular hypertrophy. Hypertension. 2014，63(1):128-135. 
3. Shang W, Lu FJ, Sun T, Xu JJ, Li LL, Wang YR, Wang G, Chen LY, Wang XH, Mark B. Cannell, Wang SQ, Cheng HP. Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Circulation Research. 2014, 114(3):412-420.
4. Ye AY, Liu QR, Li CY, Zhao M, Qu H. Human transporter database: comprehensive knowledge and discovery tools in the human transporter genes. PLoS One. 2014, 9(2):e88883.
5. Zhang SJ, Liu CJ, Yu, Zhong X, Chen JY, Yang XZ, Peng J, Yan S, Wang C, Zhu X, Xiong J, Zhang YE, Tan CM, Li CY. Evolutionary interrogation of human biology in well-annotated genomic framework of rhesus macaque. Molecular Biology and Evolution. 2014, 31 (5): 1309-1324. 
6. Chen JY, Peng Z, Zhang R, Yang XZ, Tan CM, Fang H, Liu CJ, Zhang YE, Shi M, Ye ZQ, Deng M, Zhang X, Li CY. RNA editome in rhesus macaque shaped by purifying selection. PLoS Genetics. 2014, 10(4):e1004274.
7. Liu LN, Zhu FP, Song MY, Kang XJ, Shang SJ, Zhang XY, Xu HD, Teng SS, Liu B, Kuo ST, Liu W, Li ML, Zhou L, Jiao RY, Wang CH, Wang SR, Yang H, Zhang B, Zhou Z, Xu ZQ. Effect of cocaine on ion channels and glutamatergic EPSCs in noradrenergic locus coeruleus neurons. J Mol Neurosci. 2014 , 53(3):345-51.
8. Wang L, Shang SJ, Kang XJ, Teng SS, Zhu FP, Liu B, Wu QH, Li ML, Liu W, Xu HD, Zhou L, Jiao RY, Dou HQ, Zuo PL, Zhang XY, Zheng LH, Wang SR, Wang CH, Zhou Z. Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine. Nat Commun. 2014, 5:3925.
9. Sun L, Chen C, Jiang B, Li Y, Deng Q, Sun M, An X, Yang X, Yang Y, Zhang R, Lu Y, Zhu DS, Huo Y, Feng GS, Zhang Y, Luo J. Grb2-associated binder 1 is essential for cardioprotection against ischemia/reperfusion injury. Basic Res Cardiol. 2014, 109(4):420.
10. Zong W, Huang X, Zhang C, Yuan T, Zhu LL, Fan M, Chen L. Shadowless-illuminated variable-angle TIRF (siva-TIRF) microscopy for the observation of spatial-temporal dynamics in live cells. Biomed Opt Express. 2014, 5(5):1530-1440.
11. Liang K, Du W, Lu J, Li F, Yang L, Xue Y, Hille B, Chen L. Alterations of the Ca²？ signaling pathway in pancreatic beta-cells isolated from db/db mice. Protein Cell. 2014, 5(10):783-794.
12. Yan J, Chen R, Liu P, Gu Y. Docosahexaenoic acid attenuates hypoxic pulmonary vasoconstriction by activating the large conductance Ca2+-activated K+ currents in pulmonary artery smooth muscle cells. Pulm Pharmacol Ther. 2014, 28(1):9-16.
13. Wang H, Xu X, Fassett J, Kwak D, Liu X, Hu X, Falls TJ, Bell JC, Li H, Bitterman P, Bache RJ, Chen Y. Double-stranded RNA–dependent protein kinase deficiency protects the heart from systolic overload-Induced congestive heart failure. Circulation. 2014, 129(13):1397-1406.
14. Li Y, Zheng S, Liang X, Jin Y, Wu Y, Bai H, Liu R, Dai Z, Liang Z, Shi T. Doping hydroxylated cationic lipid into PEGylated cerasome boosts in vivo siRNA transfection efficacy. Bioconjug Chem. 2014, 25(11):2055-2066.
15. Wei Z, Li X, Zhao D, Yan H, Hu Z, Liang Z, Li Z. Flow-through cell electroporation microchip integrating dielectrophoretic viable cell sorting. Anal Chem. 2014, 86(20):10215-10222.
16. Liu X, Zhou J, Yu T, Chen C, Cheng Q, Sengupta K, Huang Y, Li H, Liu C, Wang Y, Posocco P, Wang M, Cui Q, Giorgio S, Fermeglia M, Qu F, Pricl S, Shi Y, Liang Z, Rocchi P, Rossi JJ, Peng L. Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems. Angew Chem Int Ed Engl. 2014, 53(44):11822-11827.
17. Wei Z, Zheng S, Wang R, Bu X, Ma H, Wu Y, Zhu L, Hu Z, Liang Z, Li Z. A flexible microneedle array as low-voltage electroporation electrodes for in vivo DNA and siRNA delivery. Lab Chip. 2014, 14(20):4093-4102.
18. Huang W, Zhao M, Wei N, Wang X, Cao H, Du Q, Liang Z. Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients. PLoS One. 2014, 9(5):e96490.
19. Li Y, Cheng Q, Jiang Q, Huang Y, Liu H, Zhao Y, Cao W, Ma G, Dai F, Liang X, Liang Z, Zhang X. Enhanced endosomal/lysosomal escape by distearoyl phosphoethanolamine-polycarboxybetaine lipid for systemic delivery of siRNA. J Control Release. 2014,176:104-114.
20. Yang F, Zhou L, Wang Q, You X, Li Y, Zhao Y, Han X, Chang Z, He X, Cheng C, Wu C, Wang WJ, Hu FY, Zhao T, Li Y, Zhao M, Zheng GY, Dong J, Fan C, Yang J, Meng X, Zhang Y, Zhu X, Xiong J, Tian XL, Cao H. NEXN inhibits GATA4 and leads to atrial septal defects in mice and humans. Cardiovasc Res. 2014, 103(2):228-237.
21. Guo WT, Wang XW, Wang Y. Micro-management of pluripotent stem cells. Protein Cell. 2014, 5(1):36-47.
22. Woo AY, Jozwiak K, Toll L, Tanga MJ, Kozocas JA, Jimenez L, Huang Y, Song Y, Plazinska A, Pajak K, Paul RK, Bernier M, Wainer IW, Xiao RP. Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of beta2-adrenoceptor. Journal of Biochemistry. 2014, 289(28):19351-63.
23. Liu P, Long L, Xiong K, Yu B, Chang N, Xiong JW, Zhu Z and Liu D. Inheritable and conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system. Cell Res. 2014, 24(7):886-889.
24. Bu Y, Su F, Wang X, Gao H, Lei L, Chang NN, Wu Q, Hu K, Zhu X, Chang ZJ, Meng K and Xiong JW. Ptpn9 regulates primitive erythroid cell development through Stat3 dephosphorylation in zebrafish. J Cell Sci. 2014, 127(Pt 12):2761-2770.
25. Yan B, Han P, Pan L, Lu W, Xiong JW, Zhang M, Zhang W, Li L and Wen ZL. IL-1β and ROS differentially regulate neutrophil directional migration and basal random motility in zebrafish injury-induced inflammation model. J Immunol. 2014, 192(12):5998-6008.
26. Han P, Zhou XH, Chang N, Xiao CL, Yan S, Ren H, Yang XZ, Zhang ML, Wu Q, Tang Y, Diao JP, Zhu X, Zhang CM, Li CY, Cheng H, and Xiong JW. Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Res. 2014, 24(9):1091-1107.
27. Kang, X., H. Xu, S. Teng, X. Zhang, Z. Deng, L. Zhou, P. Zuo, B. Liu, Q. Wu, L. Wang, M. Hu, H. Dou, W. Liu, F. Zhu, Q. Li, S. Guo, J. Gu, Q. Lei, J. Lu, Y. Mu, M. Jin, S. Wang, W. Jiang, K. Liu, C. Wang, W. Li, K. Zhang, and Z. Zhou. Dopamine release from transplanted neural stem cells in Parkinsonian rat striatum in vivo. Proc Natl Acad Sci U S A. 2014, 111(44):15804-15809.
28. Shang SJ,Wang CH, Liu B, Wu QH, Zhang QF, Liu W,Zheng LH, Xu HD, Kang XJ, Zhang XY, Yeshi Wang, Hui Zheng,Wang SR, Xiong W, Liu T, Zhou Z. Extracellular Ca2+per se inhibits quantal size of catecholamine releasein adrenal slice chromaffin cells. Cell Calcium. 2014,56(3): 202–207.
29. Kuo ST , Wu QH, Liu B, Xie ZL, Wu X, Shang SJ, Zhang XY, Kang XJ, Liu LN, Zhu PF, Wang YS, Hu MQ, Xu, L. HD , Liu B, Chai ZY, Zhang QF, Liu W, Teng SS,Wang HC , Guo N , Dou HQ, Zuo PL, Zheng LH, Zhang CX, Zhu DS,Wang L, Wang SR, Zhou Z. Importing, caring, breeding, genotyping, and phenotyping a genetic mouse in a Chinese university. J Mol Neurosci 2014,53(3):487–492.
30. Li YT, Zhang SH, Wang L, Xiao RR, Liu W, Zhang XW, Zhou Z, Amatore C, Huang WH. Nanoelectrode for amperometric monitoring of individual vesicular exocytosis inside single synapses. Angew. Chem. Int. Ed., 2014, 53(46): 12456-12460
31. Yang YM, Wang W, Fedchyshyn MJ, Zhou Z, Ding JP, Wang LY. Enhancing the fidelity of neurotransmission by activity-dependent facilitation of presynaptic K+ currents. Nat Commun. 2014, 5:4564.
32. Wang L, Zhang XY, Xu HD, Zhou L, Jiao RY, Liu W, Zhu FP, Kang XJ, Liu B, Teng SS, Wu QH, Li ML, Dou HQ, Wang CH, Zuo PL, Wang SR, Zhou Z. Temporal components of cholinergic terminal to dopaminergic terminal transmission in dorsal striatum slices of mice. J Physiol. 2014, 592(Pt 16):3559-3576.
33. He A, Gu F, Hu Y, Ma Q, Ye LY, Akiyama JA, Visel A, Pennacchio LA, Pu WT. Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. Nat Commun. 2014, 5:4907.
34. Hou TT, Wang XH, Ma Q, Cheng HP. Mitochondrial flashes: new insights into mitochondrial ROS signalling and beyond. J Physiol. 2014, 592(Pt 17):3703-3713.
35. Cheng HP, Wang W, Wang XH, Sheu SS, Dirksen RT, Dong MQ. Cheng et al. reply. Nature. 2014, 514(7523):e14-15.
36. Yan W, Zhang F, Zhang R, Zhang X, Wang Y, Zhou F, Xia Y, Liu P, Gao C, Wang H, Zhang L, Zhou J, Gao F, Gao E, Koch WJ, Wang H, Cheng HP, Qu Y, Tao L. Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. J Mol Cell Cardiol. 2014, 74:183-192.
37. Li S, Cheng HP, Tomaselli GF, Li RA. Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: direct evidence of functional Ca2+-induced Ca2+ release. Heart Rhythm. 2014, 11(1):133-140.
38. Hou Y, Ghosh P, Wan R, Ouyang X, Cheng HP, Mattson MP, Cheng A. Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1-42 on neural progenitor cell proliferation. Neurobiol Aging. 2014, 35(5):975-989.
39. Zhang W, Li K, Zhu X, Wu D, Shang W, Yuan X, Huang Z, Zheng M, Wang X, Yang D, Liu J, Cheng HP. Subsarcolemmal mitochondrial flashes induced by hypochlorite stimulation in cardiac myocytes. Free Radic Res. 2014, 48(9):1085-1094.
40. Jian CS, Hou TT, Yin RK, Cheng HP, Wang XH. Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations. Sci China Life Sci. 2014, 57(5):495-501.
41. Deng Q, Huo Y, Luo J. Endothelial mechanosensors: the gatekeepers of vascular stasis and adaptation under mechanical stress. Sci China Life Sci. 2014, 57 (8): 755–762.
42. Sun J, Lu F, He H, Shen J, Messina J, Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, Cheng HP, Yang S. STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion. J Cell Biol, 2014, 207(4):535-548
43. Liu T, Li H, Gounko N, Zhou Z, Xu A, Hong W, Han W. Detection of insulin granule exocytosis by an electrophysiology method with high temporal resolution reveals enlarged insulin granule pool in BIG3 knockout mice. Am J Physiol-Endo M. 2014, 307(7):e611-618
44. Gal D, Vandevelde W, Cheng HP, Sipido K R. Cardiovascular research as a forum for publications from China: present, past and future. Cardiovascular Research. 2014, 104(4):383-387
45. Liang S, Wang Q, Zhang W, Zhang H, Tan S, Ahmed A, Gu Y. Carbon monoxide inhibits inward rectifier potassium channels in cardiomyocytes. Nat Commun. 2014,5:4676.
46. Guo DQ, Zhang H, Tan SJ, Gu YC. Nifedipine promotes the proliferation and migration of breast cancer cells. PLos One. 2014，9(12):e113649.
47. Jiang Q, Meng X, Meng L, Chang N, Xiong J, Cao H, Liang Z. Small indels induced by CRISPR/Cas9 in the 5’ region of microRNA lead to its depletion and Drosha processing retardance. RNA Biology. 2014，11(10):1243-1249